Preliminary Scientific Program

Wednesday, 31 March 2027
11:00-14:30   Pre-Conference Workshops

Workshop 1:
Advanced Application of Ultrasonography in Spasticity Assessment and Treatment

Workshop 2:
Cryoneurolysis and Other Neurolytic Techniques

Workshop 3:
Percutaneous Dry Needling and Related Interventions for Spasticity

12:00

Registration Opens

15:00-16:50

2nd International Symposium Opening
Contemporary and Emerging Perspectives on Spasticity

15:00-15:20 Welcome: Introduction to Spasticity X and The International Spasticity Society
15:20-15:40 Neurophysiologic Prediction of Poststroke Spasticity
15:40-16:00 Lesion Characteristics & Structural Disconnectome Predicting Spasticity
16:00-16:20 Precision Spasticity Management: Matching Treatment to Patient Phenotype
16:20-16:40 Is Spasticity Maladaptive Plasticity?
16:40-16:50 Q & A
16:50-17:20

  Break

17:20-19:30

General Session 2
Clinical Pearls: Electromyography and Ultrasonography in Spasticity Management

17:20-17:40 Revisiting the Role of Surface Electromyography in Spasticity Assessment
17:40-18:00 Electromyographic Correlates of Ultrasonographic Findings in Spasticity
18:00-18:20 Clinical Correlates of Ultrasonographic Observations to Optimize Outcomes in Spasticity Management
18:20-18:40 Ultrasonographic Assessment of Trunk and Proximal Limb Muscles
18:40-18:50 Q & A
18:50-19:20 ISS Lifetime Achievement Award Lecture
19:20-19:30 Q & A and Presentation of Award
19:30-21:30 Welcome Reception and Networking • Exhibits and Poster Hall Open
Thursday, 1 April 2027
08:00-10:05

General Session 3
Considerations in Pediatric Spasticity

08:00-08:15 Opening Remarks
08:15-08:35 Transition of Spasticity care from Pediatrics to Adults: Challenges and Solutions
08:35-08:55 Postural Stability to Assess Outcomes of Botulinum Toxin Treatment of Spasticity in Children with Cerebral Palsy
08:55-09:15 Non-Invasive Assessment of Muscle Spasticity in Children Using Near-infrared Spectroscopy
09:15-09:25 Q & A
09:25-10:05 Debate: Pediatric Topic TBD
10:05-10:50

 Break • Educational Theatre • Exhibit and Poster Hall Open

10:50-12:00

General Session 4
Acute Management of Spasticity

10:50-11:10 Early Recognition and Intervention for Poststroke Spasticity (The American Heart Association Stroke Council Statement)
11:10-11:30 The Benefits of Early Intervention Using Botulinum Toxin
11:30-11:50 Does Spasticity Really Begin Early?
11:50-12:00 Q & A
12:00-14:00

 Lunch • Industry-Sponsored Session • Exhibit and Poster Hall Open

14:00-15:30   Parallel Session 1
Focus on Persons With the Lived Experience of Spasticity


  Parallel Session 2
Gait


14:00-14:20 Aligning Minds in Spasticity Care
Instrumented Assessment of Spastic Gait
14:20-14:40 Patient and Caregiver Burden and The Lived Experience of Spasticity
Spasticity’s Impact on Gait Speed
14:40-15:00 The Spasticity Syndrome and its Multimodal Management are a Patient-Centric Approach
Hemiplegic Spastic Gait and the Effect of Phenol Neurolysis
15:00-15:20 Patient Perspectives on Adherence to Botulinum Toxin Therapy in Spasticity
Effectiveness of Botulinum Toxin A on Gait and Fatigue in Persons With Multiple Sclerosis
15:20-15:30 Q & A
Q & A
15:30-16:15   Break • Educational Theatre • Exhibit and Poster Hall Open
16:15-17:45   Parallel Session 3
Spinal Origin Spasticity


  Parallel Session 4
Neuro-Orthopedics


16:15-16:35 Spasticity After Traumatic Spinal Cord Injury: Implications for Recovery
Contemporary Management of Equinovarus Deformity
16:35-16:55 Reticulospinal Contributions to Spinal-Origin Spasticity
Management of Post-Stroke Flexed Elbow Deformity
16:55-17:15 Multifocal Spasticity Management in Persons with Spinal Cord Injuries: Focus on Proximal Musculature
Percutaneous Tenotomy for Spasticity Management
17:15-17:35 Bone Health and Spasticity After a Spinal Cord Injury
Emerging Surgical Interventions for Spasticity
17:35-17:45 Q & A
Q & A
Friday, 2 April 2027
08:30-12:00   Parallel Session 5
Spasticity Assessment and Therapeutic Exercise Modalities


  Parallel Session 6
Neurolysis and Other Procedures


08:30-08:40 Opening Remarks
Opening Remarks
08:40-09:00 The Complexities of Conceptualizing, Defining, and Measuring Spasticity
Developments in Cryoneurolysis
09:00-09:20 Exercise and Spasticity
Long-term Outcome of Cryoneurolysis
09:20-09:40 Effect of Additional Rehabilitation After Botulinum Toxin-A on Upper Limb Activity in Chronic Stroke
Appropriate Use of Diagnostic Nerve Block
09:40-10:00 Impact of Pre-Conditioning Serial Casting on Botulinum Toxin Therapy
Dry Needling
10:00-10:10 Q & A
Q & A
10:10-10:55   Break • Educational Theatre • Exhibit and Poster Hall Open
10:55-12:05   Parallel Session 7
Technology Forum: Assessment and Treatment


  Parallel Session 8
Neurolysis and Other Procedures


10:55-11:15 Robotics for Spasticity Assessment and Treatment
Opening Remarks
11:15-11:35 Wearable Sensor Technology
Debate: Phenol Neurolysis or Cryoneurolysis?
11:35-11:55 Extracorporeal Shock Wave Therapy for Post-Stroke Spasticity
11:55-12:05 Q & A
Q & A
12:05-14:00   Lunch • Industry-Sponsored Session • Exhibit and Poster Hall Open
14:00-15:30   Parallel Session 9
Artificial Intelligence


  Parallel Session 10
Botulinum Toxins I


14:00-14:20 The Basics of Artificial Intelligence
Short- and Long-Acting Botulinum Toxins
14:20-14:40 Artificial Intelligence for Spasticity Management
Botulinum Toxin in Pain-Related Post-Stroke Limb Spasticity
14:40-15:00 Natural Language Processing and Machine Learning in Spasticity Management
Unpleasant Sensations in Spasticity & the Modulatory Role of Botulinum Toxin
15:00-15:20 Machine Learning Algorithm Prediction in Spasticity Assessment
Use of Botulinum Toxin as a Treatment of Hemiplegic Shoulder Pain Syndrome
15:30-16:15  Break • Educational Theatre • Exhibit and Poster Hall Open
16:15-17:45   Parallel Session 11
Oral Presentations


  Parallel Session 12
Neuromodulation


16:15-16:35 Oral Presentation 1
Oral Presentation 2
European Expert Consensus on Improving Patient Selection for Chemodenervation and Intrathecal Therapy
16:35-16:55 Oral Presentation 3
Oral Presentation 4
Revisiting the Role of Intrathecal Therapies in Comprehensive Spasticity Management
16:55-17:15 Oral Presentation 5
Oral Presentation 6
Advanced Techniques to Optimize Intrathecal Therapies for Spasticity
17:15-17:35 Oral Presentation 7
Oral Presentation 8
Radiofrequency Interventions for Spasticity
17:35-17:45 Q & A
Q & A
Saturday, 3 April 2027
09:00-10:30   Parallel Session 11
Botulinum Toxins II


  Parallel Session 12
Neuromodulation II


09:00-09:20 Managing the Patient with Concurrent Multiple Indications for Botulinum Toxin
Repetitive Magnetic Stimulation for Treating Upper Limb Spasticity After Stroke
09:20-09:40 Effects of Increasing Botulinum Toxin Doses on Gait
Electrical Stimulation Therapy for Post-Stroke Spasticity
09:40-10:00 Safety and Efficacy of Newer Botulinum Toxins in the Treatment of Post-Stroke Upper Limb Spasticity
High-Frequency Epidural Electrical Stimulation in Managing Spasticity in Spinal Cord Injury
10:00-10:20 The Impact of Botulinum Toxins on Abnormal Flexor Synergies
Pre- and Postsynaptic Inhibition of Spinal Spasticity by Transcutaneous Spinal Cord Stimulation
10:20-10:30 Q & A
Q & A
10:30-10:50   Break
10:50-13:00 General Session 5
Focus on Muscle in Spasticity
Best Paper and Poster Awards
10:50-10:55 Muscle Changes in Spasticity
10:55-11:15 Relationship Between Spasticity, Muscle Stiffness and Fibrosis – Insights From Treatment With Hyaluronidase
11:15-11:35 Impact of Long-Term Botulinum Toxin A Treatment on Muscle Morphology and Stiffness
11:35-11:55 Muscle Type-Specific Effects of Botulinum Toxin on Muscle Growth and Contractile Function
11:55-12:15 Direct Myosin Inhibition as a Drug Target for Treating Spasticity
12:15-12:35 The Effect of Excitation-Contraction Coupling Inhibitors on the Action of Botulinum Neurotoxins
12:35-12:45 Q & A
12:45-12:55 Best Oral Paper and Poster Awards Presentation
12:55-13:00   Closing Remarks